Ethyl quinoline-2-carboxylic acid

Ethyl quinoline-2-carboxylic acid - Names and Identifiers

Name	ethyl quinoline-2-carboxylate
Synonyms	ethyl quinoline-2-carboxylate Ethyl quinoline-2-carboxylic acid 2-Quinoline carbocylic acid ethyl ester 2-Quinolinecarboxylic acid, ethyl ester
CAS	4491-33-2

Ethyl quinoline-2-carboxylic acid - Physico-chemical Properties

Molecular Formula	C12H11NO2
Molar Mass	201.22
Density	1.175±0.06 g/cm3(Predicted)
Melting Point	30-33 °C(Solv: ethyl ether (60-29-7))
Boling Point	180 °C(Press: 14 Torr)
pKa	2.07±0.40(Predicted)
Storage Condition	2-8°C

Ethyl quinoline-2-carboxylic acid - Reference Information

Overview

Ethyl quinolin-2-carboxylate is an intermediate for the synthesis of quinolin-2-carboxylic acids. Quinolin-2-formic acid is a very important intermediate in organic synthesis, which is mainly used in the fields of organic synthesis, medicine and pesticides. In the field of synthetic chemistry, quinolin-2-formic acid is mainly used as a raw material for the synthesis of quinolin-2-methanonitrile and quinolin-2-methyl formate, and quinolin-2-methanonitrile is the synthesis of quinolinyl pyrimidine, quinolinyl thiazole, quinolinyl triazole and other quinolinyl heterocyclic compounds intermediates; quinolin-2-methyl formate is also an important raw material for the synthesis of fine chemicals. In medicine, the synthetic quinoline polyamine derivatives such as Luo Wen have a better protective effect on adrenal pheochromocytoma, and the activity of some compounds is higher than that of nimodipine. In the field of pesticide synthesis, quinoline -2-formic acid is an important precursor for the synthesis of organotin carboxylic acid esters, and organotin carboxylic acid esters have good insecticidal and bactericidal effects. Because quinolin-2-formic acid has many uses, its synthesis method has also become a research hotspot.

Last Update：2024-04-09 21:01:54